DDX1

Across TCGA patient cohorts, DDX1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,979 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDX1-associated genes across cancer lineages are MGAT1, CSF3R, and HMOX1. Each is linked with DDX1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DDX1-to-partner and partner-to-DDX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX1 versus MGAT1 in GBM, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX1→partner) and Y-score (partner→DDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MGAT1 →	-0.419	-0.293	<.001	<.001	3	6
LSCC	CSF3R →	-1.230	-0.205	<.001	<.001	3	6
GBM	HMOX1 →	-0.910	-0.191	<.001	<.001	3	5
GBM	SOD2 →	-1.674	-0.298	<.001	<.001	3	5
COAD	PLEK →	-0.776	-0.125	.009	.007	3	5
CCRCC	PTAFR →	-0.731	-0.173	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,979 associations by consensus.

DDX1 vs MGAT1 — GBM

Explore this scatter interactively →