DDX1

Across TCGA cell cohorts, DDX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,968 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DDX1-associated GO terms across cancer lineages are Mitotic sister chromatid cohesion, DNA replication, and DNA-templated DNA replication. Each is linked with DDX1 in more than 16 cancer types. Because this analysis shows association rather than direction, both DDX1-to-partner and partner-to-DDX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic sister chromatid cohesion grouped by DDX1-low versus DDX1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX1→partner) and Y-score (partner→DDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Mitotic sister chromatid cohesion →	+0.113	+0.816	<.001	<.001	3	17
BLOOD_Myeloma	DNA replication →	+0.109	+0.649	<.001	.006	3	16
BLOOD_Myeloma	DNA-templated DNA replication →	+0.118	+0.646	<.001	.006	3	16
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.165	+1.335	<.001	<.001	3	15
OESOPHAGUS	Meiotic sister chromatid cohesion →	+0.184	+0.942	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle →	+0.080	+1.298	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,968 associations by consensus.

Mitotic sister chromatid cohesion by DDX1 expression — KIDNEY

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