DDTL

Across TCGA patient cohorts, DDTL RNA expression is significantly associated with the RNA expression of many other genes, with 18,725 significant associations in total. UVM shows the largest number of these associations.

The most reproducible DDTL-associated genes across cancer lineages are ZNF692, ZNF789, and PPIL2. Each is linked with DDTL in more than 30 cancer types. Because this analysis shows association rather than direction, both DDTL-to-partner and partner-to-DDTL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDTL versus ZNF692 in KIRP, with a Pearson correlation of 0.56.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDTL→partner) and Y-score (partner→DDTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	ZNF692 →	+1.018	+0.564	<.001	<.001	3	31
SCLC	ZNF789 →	+1.075	+0.720	<.001	<.001	3	31
SCLC	PPIL2 →	+0.769	+0.901	<.001	<.001	3	31
UVM	LRP5L →	+1.096	+0.668	<.001	<.001	3	31
ACC	TRMU →	+1.115	+1.190	<.001	<.001	3	31
ACC	DDT →	+1.698	+1.146	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,725 associations by consensus.

DDTL vs ZNF692 — KIRP

Explore this scatter interactively →