DDT

Across TCGA pan-cancer cohorts, DDT Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated DDT data layer compared with 26 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher DDT Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DDT expression acts as an unfavorable survival marker.

LUSC are the cancer types where DDT Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.131	0.776	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

DDT–LUSC (OS)

Open the LUSC breakdown →