DDRGK1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DDRGK1 mutation is significantly associated with the RNA expression of many other genes, with 291 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDRGK1-associated genes across cancer lineages are RAB1AP2, LINC01034, and RNU6-651P. Each is linked with DDRGK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDRGK1-to-partner and partner-to-DDRGK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDRGK1→partner) and Y-score (partner→DDRGK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRAB1AP2 →+0.060+5.655.003.00432
COADLINC01034 →+0.197+4.516<.001.00932
STADRNU6-651P →+0.480+5.187.001.00732
UCECIGHD1-26 →+0.999+3.806<.001<.00132
UCECRNU6ATAC30P →+0.390+2.294<.001.00632
UCECRNU6-1077P →+0.531+2.381<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 291 associations by consensus.

Exploration