Across TCGA cell cohorts, DDRGK1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible DDRGK1-associated genes across cancer lineages are C12orf40, ASB17, and OR2M4. Each is linked with DDRGK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDRGK1-to-partner and partner-to-DDRGK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDRGK1→partner) and Y-score (partner→DDRGK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	C12orf40 →	+0.011	+4.029	<.001	.009	3	2
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1
OVARY	OR2M4 →	+0.078	+4.700	<.001	.002	3	1
LARGE_INTESTINE	ASZ1 →	+0.045	+3.920	<.001	.005	3	1
BLOOD_Lymphoma	F9 →	+0.035	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	TMEM207 →	+0.622	+4.523	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

DDRGK1 survival (RNA) · tumor vs normal (RNA) · all DDRGK1 data types