Across TCGA patient cohorts, DDR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,615 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDR1-associated proteins across cancer lineages are CTNNA1, CTNND1, and NELFB. Each is linked with DDR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DDR1-to-partner and partner-to-DDR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDR1→partner) and Y-score (partner→DDR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CTNNA1 →	+0.279	+0.575	.004	.007	2	6
LSCC	CTNND1 →	+0.276	+0.929	<.001	<.001	3	5
LUAD	NELFB →	+0.173	+0.410	.004	.004	3	5
LSCC	PLCG2 →	-0.440	-0.703	<.001	<.001	3	5
GBM	GTF3C1_S739 →	+0.338	+0.395	<.001	.005	3	5
HNSC	RXRB →	+0.414	+0.830	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,615 associations by consensus.

Exploration

DDR1 survival (RNA) · tumor vs normal (RNA) · all DDR1 data types