Across TCGA patient cohorts, DDR1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,735 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDR1-associated genes across cancer lineages are GNG2, CD209, and IL16. Each is linked with DDR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DDR1-to-partner and partner-to-DDR1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDR1→partner) and Y-score (partner→DDR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GNG2 →	-0.852	-0.349	<.001	<.001	3	6
LSCC	CD209 →	-0.616	-0.492	<.001	<.001	3	6
PDAC	IL16 →	-0.631	-0.419	<.001	<.001	3	6
HNSC	POU2F2 →	-0.743	-0.312	.002	.002	3	6
OV	CD79B →	-0.969	-0.348	.007	.007	3	6
UCEC	CHRDL1 →	-1.553	-0.298	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,735 associations by consensus.

Exploration

DDR1 survival (RNA) · tumor vs normal (RNA) · all DDR1 data types