Across TCGA patient cohorts, DDR1 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,408 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDR1-associated proteins across cancer lineages are LRRC1, TLN1, and LSR. Each is linked with DDR1 in more than 8 cancer types. Because this analysis shows association rather than direction, both DDR1-to-partner and partner-to-DDR1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDR1→partner) and Y-score (partner→DDR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LRRC1 →	+0.422	+0.466	<.001	<.001	3	9
PDAC	TLN1 →	-0.341	-0.450	<.001	<.001	3	8
LUAD	LSR →	+0.430	+0.373	.001	<.001	3	8
OV	CDH1 →	+0.529	+0.397	<.001	.001	3	7
GBM	CLIC2 →	-0.496	-0.241	<.001	<.001	3	7
UCEC	SPINT1 →	+0.700	+0.338	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,408 associations by consensus.

Exploration

DDR1 survival (RNA) · tumor vs normal (RNA) · all DDR1 data types