Across TCGA cell cohorts, DDR1 mutation is significantly associated with the RNA expression of many other genes, with 275 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DDR1-associated genes across cancer lineages are OR1L3, DAO, and LCE1D. Each is linked with DDR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDR1-to-partner and partner-to-DDR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDR1→partner) and Y-score (partner→DDR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR1L3 →	+0.031	+3.444	<.001	.003	3	2
OVARY	DAO →	+0.047	+3.263	<.001	.006	3	1
OVARY	LCE1D →	+0.030	+3.807	<.001	.009	3	1
OVARY	IFNA17 →	+0.010	+3.807	<.001	.009	3	1
OVARY	PPIAL4D →	+0.111	+3.841	.001	.003	3	1
OVARY	ARMH2 →	+0.042	+4.965	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 275 associations by consensus.

Exploration

DDR1 survival (RNA) · tumor vs normal (RNA) · all DDR1 data types