DDOST

Across TCGA cell cohorts, DDOST RNA expression is significantly associated with the go_rna of many other GO terms, with 5,175 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDOST-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, Glycoside catabolic process, and Glycolipid catabolic process. Each is linked with DDOST in more than 16 cancer types. Because this analysis shows association rather than direction, both DDOST-to-partner and partner-to-DDOST results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by DDOST-low versus DDOST-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDOST→partner) and Y-score (partner→DDOST) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of protein exit from endoplasmic reticulum →	+0.142	+0.790	.003	.002	2	17
BLOOD_Leukemia	Glycoside catabolic process →	+0.164	+0.540	<.001	<.001	3	15
SOFT_TISSUE	Glycolipid catabolic process →	+0.184	+0.899	<.001	<.001	3	15
BONE	Carbohydrate derivative catabolic process →	+0.068	+0.573	<.001	<.001	3	15
SOFT_TISSUE	Peptide hormone processing →	+0.157	+0.752	.001	<.001	3	14
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.156	+0.832	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,175 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by DDOST expression — LIVER

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