Across TCGA cell cohorts, DDO RNA expression is significantly associated with the go_rna of many other GO terms, with 3,502 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DDO-associated GO terms across cancer lineages are Antigen processing and presentation of endogenous antigen, CD8-positive, alpha-beta T cell activation, and Antigen processing and presentation of endogenous peptide antigen. Each is linked with DDO in more than 12 cancer types. Because this analysis shows association rather than direction, both DDO-to-partner and partner-to-DDO results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDO→partner) and Y-score (partner→DDO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Antigen processing and presentation of endogenous antigen →	+0.245	+1.589	<.001	.004	3	13
PANCREAS	CD8-positive, alpha-beta T cell activation →	+0.159	+0.800	<.001	<.001	3	13
BREAST	Antigen processing and presentation of endogenous peptide antigen →	+0.226	+0.654	<.001	<.001	3	12
SOFT_TISSUE	Regulation of tolerance induction dependent upon immune response →	+1.128	+1.430	<.001	<.001	2	13
LIVER	Antigen processing and presentation of endogenous peptide antigen via MHC class I →	+0.274	+1.867	<.001	.002	3	12
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic pattern recognition receptor signaling pathway →	+0.077	+0.321	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,502 associations by consensus.

Exploration

DDO survival (RNA) · tumor vs normal (RNA) · all DDO data types