DDN

Across TCGA patient cohorts, DDN RNA expression is significantly associated with the protein abundance of many other proteins, with 22,342 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDN-associated proteins across cancer lineages are UTP18, NOC4L, and CHORDC1. Each is linked with DDN in more than 4 cancer types. Because this analysis shows association rather than direction, both DDN-to-partner and partner-to-DDN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDN versus UTP18 in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDN→partner) and Y-score (partner→DDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UTP18 →	+0.345	+0.368	<.001	<.001	3	5
BRCA	NOC4L →	+0.420	+0.657	<.001	<.001	3	5
BRCA	CHORDC1 →	+0.434	+0.556	<.001	<.001	3	5
LSCC	DCAF13 →	+0.349	+0.446	<.001	<.001	3	4
LSCC	DNAJC2 →	+0.478	+0.502	<.001	<.001	3	4
BRCA	ASL →	-0.478	-0.560	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,342 associations by consensus.

DDN vs UTP18 — LSCC

Explore this scatter interactively →