DDN

Across TCGA cell cohorts, DDN RNA expression is significantly associated with the RNA expression of many other genes, with 8,558 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DDN-associated genes across cancer lineages are POLR1B, TFAP4, and TRAP1. Each is linked with DDN in more than 10 cancer types. Because this analysis shows association rather than direction, both DDN-to-partner and partner-to-DDN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDN versus POLR1B in BONE, with a Pearson correlation of 0.56.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDN→partner) and Y-score (partner→DDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	POLR1B →	+1.072	+1.355	<.001	.004	2	11
BONE	TFAP4 →	+1.644	+1.703	<.001	<.001	3	10
BONE	TRAP1 →	+1.702	+1.460	<.001	.002	3	9
BONE	ANKRD13B →	+1.504	+1.260	<.001	<.001	2	9
BLOOD_Lymphoma	KLF16 →	+0.918	+2.009	<.001	<.001	3	8
BLOOD_Lymphoma	CLUH →	+1.282	+1.403	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,558 associations by consensus.

DDN vs POLR1B — BONE

Explore this scatter interactively →