DDIT4

Across TCGA patient cohorts, DDIT4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,850 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDIT4-associated proteins across cancer lineages are RHOT1, S100A9, and EEF2_S502. Each is linked with DDIT4 in more than 4 cancer types. Because this analysis shows association rather than direction, both DDIT4-to-partner and partner-to-DDIT4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDIT4 versus RHOT1 in UCEC, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDIT4→partner) and Y-score (partner→DDIT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RHOT1 →	-0.328	-1.537	<.001	<.001	3	5
BRCA	S100A9 →	+1.224	+1.030	.001	.001	3	5
BRCA	EEF2_S502 →	+0.942	+1.307	<.001	<.001	3	5
BRCA	ERO1A →	+0.585	+1.028	<.001	.001	3	5
LSCC	FSCN1 →	+0.662	+0.925	<.001	<.001	3	5
HNSC	NDRG1 →	+0.828	+1.392	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,850 associations by consensus.

DDIT4 vs RHOT1 — UCEC

Explore this scatter interactively →