DDIT4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DDIT4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible DDIT4-associated genes across cancer lineages are MOS. Each is linked with DDIT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDIT4-to-partner and partner-to-DDIT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MOS grouped by DDIT4-low versus DDIT4-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDIT4→partner) and Y-score (partner→DDIT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASMOS →+0.018+5.000.004.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MOS by DDIT4 expression — PANCREAS

Box plot of MOS in DDIT4-low vs DDIT4-high samples in PANCREAS.

Explore this box plot interactively →

Exploration