DDIAS

Across TCGA pan-cancer cohorts, DDIAS Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DDIAS data layer compared with 28 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher DDIAS Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated DDIAS expression acts as an unfavorable survival marker.

OV, LUAD, and LGG are the cancer types where DDIAS Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	III,IV	0.237	0.533	.017	36	view →
LUAD	OS	Median	III,IV	0.223	0.677	.006	6	view →
LGG	DFS	Median	All	0.376	0.731	.041	5	view →
COAD	DFS	Median	II,III,IV	0.220	0.503	.031	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DDIAS–OV (DFS)

Open the OV breakdown →