DDB2

Across TCGA patient cohorts, DDB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,729 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DDB2-associated proteins across cancer lineages are DDB2_S26, FDXR, and SUPV3L1. Each is linked with DDB2 in more than 8 cancer types. Because this analysis shows association rather than direction, both DDB2-to-partner and partner-to-DDB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDB2 versus DDB2_S26 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDB2→partner) and Y-score (partner→DDB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DDB2_S26 →	+0.766	+0.660	<.001	<.001	3	9
CCRCC	FDXR →	+0.574	+0.568	<.001	<.001	3	6
LUAD	SUPV3L1 →	-0.445	-0.333	<.001	<.001	3	5
LSCC	ARFGEF2 →	-0.246	-0.433	<.001	<.001	3	5
PDAC	HM13 →	-0.536	-0.283	.004	.004	3	5
LUAD	PPIF →	-0.419	-0.319	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,729 associations by consensus.

DDB2 vs DDB2_S26 — LSCC

Explore this scatter interactively →