DDB1

Across TCGA patient cohorts, DDB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,455 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDB1-associated proteins across cancer lineages are BTK, CRELD2, and TXNDC5. Each is linked with DDB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DDB1-to-partner and partner-to-DDB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDB1 versus BTK in LSCC, with a Pearson correlation of -0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDB1→partner) and Y-score (partner→DDB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BTK →	-0.343	-0.372	<.001	<.001	3	5
GBM	CRELD2 →	-0.641	-0.380	<.001	<.001	3	5
LSCC	TXNDC5 →	-0.500	-0.412	<.001	<.001	3	4
GBM	WAS →	-0.376	-0.178	<.001	.001	3	4
HNSC	PSMB10 →	-0.394	-0.545	.003	.001	3	4
GBM	RASSF5 →	-0.560	-0.294	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,455 associations by consensus.

DDB1 vs BTK — LSCC

Explore this scatter interactively →