Across TCGA patient cohorts, DDAH2 mutation is significantly associated with the RNA expression of many other genes, with 1,653 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDAH2-associated genes across cancer lineages are RNA5SP146, AK4P5, and SRXN1. Each is linked with DDAH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDAH2-to-partner and partner-to-DDAH2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDAH2→partner) and Y-score (partner→DDAH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP146 →	+0.522	+4.867	<.001	.005	3	2
UCEC	AK4P5 →	+0.097	+2.677	.008	.002	3	2
UCEC	SRXN1 →	+0.874	+3.606	<.001	.001	3	1
UCEC	ATP1B3P1 →	+0.347	+3.392	<.001	.006	3	1
UCEC	POM121C →	+0.613	+2.754	<.001	.003	3	1
UCEC	DOC2B →	-1.132	-3.459	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,653 associations by consensus.

Exploration

DDAH2 survival (RNA) · tumor vs normal (RNA) · all DDAH2 data types