Across TCGA cell cohorts, DDAH2 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDAH2-associated genes across cancer lineages are TBC1D28, AVP, and FAM205A. Each is linked with DDAH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDAH2-to-partner and partner-to-DDAH2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDAH2→partner) and Y-score (partner→DDAH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TBC1D28 →	+0.084	+3.926	<.001	.003	3	2
LARGE_INTESTINE	AVP →	+0.049	+3.632	<.001	.003	3	1
LARGE_INTESTINE	FAM205A →	+0.028	+5.029	<.001	<.001	3	1
LARGE_INTESTINE	KLF18 →	+0.007	+3.345	<.001	.007	3	1
SKIN	DCD →	+0.103	+4.977	<.001	.007	3	1
SKIN	PRSS58 →	+0.047	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

DDAH2 survival (RNA) · tumor vs normal (RNA) · all DDAH2 data types