DDAH1

Across TCGA pan-cancer cohorts, DDAH1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated DDAH1 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher DDAH1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DDAH1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and COAD show a favorable association.

PDAC, COAD, and CCRCC are the cancer types where DDAH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.535	0.287	<.001	94	view →
COAD	DFS	Median	All	1.000	0.921	.016	36	view →
CCRCC	OS	Median	All	0.929	0.752	.006	32	view →
UCEC	DFS	Median	All	0.925	0.792	.034	14	view →
LUAD	DFS	Quartile	All	0.674	0.334	.005	10	view →
HNSC	OS	Tertile	All	0.928	1.000	.009	8	view →
GBM	DFS	Tertile	All	0.862	0.679	.021	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

DDAH1–PDAC (DFS)

Open the PDAC breakdown →