DDAH1

Across TCGA patient cohorts, DDAH1 protein abundance is significantly associated with the RNA expression of many other genes, with 22,423 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DDAH1-associated genes across cancer lineages are SERPINE1, CHDH, and GJB1. Each is linked with DDAH1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DDAH1-to-partner and partner-to-DDAH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDAH1 versus SERPINE1 in COAD, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDAH1→partner) and Y-score (partner→DDAH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SERPINE1 →	-1.895	-0.637	<.001	<.001	3	8
UCEC	CHDH →	+1.078	+0.568	<.001	<.001	3	8
GBM	GJB1 →	+1.559	+0.442	<.001	.001	3	8
OV	TMEM158 →	-1.405	-0.583	<.001	<.001	3	8
BRCA	CAB39L →	+1.199	+0.674	<.001	<.001	3	7
GBM	PLLP →	+1.170	+0.431	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,423 associations by consensus.

DDAH1 vs SERPINE1 — COAD

Explore this scatter interactively →