DDAH1

Across TCGA patient cohorts, DDAH1 mutation is significantly associated with the RNA expression of many other genes, with 2,132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDAH1-associated genes across cancer lineages are RN7SKP286, SEPTIN7P4, and LINC02427. Each is linked with DDAH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDAH1-to-partner and partner-to-DDAH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP286 grouped by DDAH1-low versus DDAH1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDAH1→partner) and Y-score (partner→DDAH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP286 →	+0.042	+3.890	<.001	.007	3	2
UCEC	SEPTIN7P4 →	+0.058	+3.547	.009	.002	3	2
UCEC	LINC02427 →	-0.235	-2.604	.009	.006	3	1
UCEC	POM121C →	+0.510	+2.556	<.001	.001	3	1
UCEC	DCP1A →	+0.705	+3.628	<.001	.001	3	1
UCEC	CWC25 →	+0.496	+3.960	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,132 associations by consensus.

RN7SKP286 by DDAH1 expression — UCEC

Explore this box plot interactively →