DDAH1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DDAH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,497 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DDAH1-associated GO terms across cancer lineages are L-arginine catabolic process, Regulation of cellular response to hypoxia, and Negative regulation of cellular response to hypoxia. Each is linked with DDAH1 in more than 14 cancer types. Because this analysis shows association rather than direction, both DDAH1-to-partner and partner-to-DDAH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-arginine catabolic process grouped by DDAH1-low versus DDAH1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDAH1→partner) and Y-score (partner→DDAH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEL-arginine catabolic process →+0.637+1.890<.001<.001315
STOMACHRegulation of cellular response to hypoxia →+0.143+2.034<.001<.001310
OVARYNegative regulation of cellular response to hypoxia →+0.152+1.611<.001<.001310
BONEEpithelial cell development →+0.171+2.556<.001<.00138
OVARYRegulation of post-translational protein modification →+0.054+0.870<.001.00438
BONEPositive regulation of blood-brain barrier permeability →+1.031+2.161.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,497 associations by consensus.

L-arginine catabolic process by DDAH1 expression — BONE

Box plot of L-arginine catabolic process in DDAH1-low vs DDAH1-high samples in BONE.

Explore this box plot interactively →

Exploration