DDA1

Across TCGA pan-cancer cohorts, DDA1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DDA1 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DDA1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DDA1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, HNSC, and LSCC are the cancer types where DDA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	II,III,IV	1.000	0.792	.015	90	view →
HNSC	OS	Median	All	0.783	0.907	.015	12	view →
LSCC	DFS	Tertile	All	0.827	0.546	.026	5	view →
CCRCC	DFS	Tertile	III,IV	0.904	0.125	.024	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DDA1–COAD (DFS)

Open the COAD breakdown →