DDA1

Across TCGA cell cohorts, DDA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,647 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DDA1-associated GO terms across cancer lineages are Negative regulation of protein localization to chromatin, Protein depolymerization, and Positive regulation of protein localization to chromatin. Each is linked with DDA1 in more than 13 cancer types. Because this analysis shows association rather than direction, both DDA1-to-partner and partner-to-DDA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization to chromatin grouped by DDA1-low versus DDA1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDA1→partner) and Y-score (partner→DDA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of protein localization to chromatin →	+0.111	+0.952	<.001	.001	3	14
SKIN	Protein depolymerization →	+0.141	+1.022	<.001	<.001	3	14
BONE	Positive regulation of protein localization to chromatin →	+0.137	+0.746	<.001	.003	3	13
STOMACH	Regulation of glycolytic process through fructose-6-phosphate →	+0.165	+0.838	.002	.003	2	12
STOMACH	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.165	+0.838	.002	.003	2	12
URINARY_TRACT	Positive regulation of early endosome to late endosome transport →	+0.116	+0.906	.005	.005	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,647 associations by consensus.

Negative regulation of protein localization to chromatin by DDA1 expression — SOFT_TISSUE

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