Across TCGA patient cohorts, DCUN1D3 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCUN1D3-associated genes across cancer lineages are eEF2, A-Raf_pS299, and FOXO3a_pS318_S321. Each is linked with DCUN1D3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCUN1D3-to-partner and partner-to-DCUN1D3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCUN1D3→partner) and Y-score (partner→DCUN1D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.346	+2.584	.008	.010	3	1
UCEC	A-Raf_pS299 →	-0.207	-2.247	<.001	.001	3	1
UCEC	FOXO3a_pS318_S321 →	-0.090	-1.502	.049	.030	3	1
UCEC	ACC1 →	+0.420	+3.000	.001	<.001	3	1
UCEC	JNK2 →	+0.229	+2.196	.001	.032	3	1
UCEC	Ku80 →	+0.226	+2.232	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

DCUN1D3 survival (RNA) · tumor vs normal (RNA) · all DCUN1D3 data types