Across TCGA pan-cancer cohorts, DCUN1D2-AS RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of DCUN1D2-AS’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where DCUN1D2-AS RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DCUN1D2-AS is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.
BLCA, HNSC, and COAD are the cancer types where DCUN1D2-AS tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DCUN1D2-AS RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.