DCTPP1

Across TCGA cell cohorts, DCTPP1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCTPP1-associated genes across cancer lineages are ADRA1A, GPR101, and NKX2-6. Each is linked with DCTPP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCTPP1-to-partner and partner-to-DCTPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADRA1A grouped by DCTPP1-low versus DCTPP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTPP1→partner) and Y-score (partner→DCTPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADRA1A →	+0.232	+4.705	<.001	.003	3	1
BLOOD_Leukemia	GPR101 →	+0.167	+4.551	<.001	.004	3	1
BLOOD_Leukemia	NKX2-6 →	+0.507	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	NPAP1 →	+0.075	+4.551	<.001	.004	3	1
BLOOD_Leukemia	PRR30 →	+0.024	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	OR10T2 →	+0.741	+4.276	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

ADRA1A by DCTPP1 expression — BLOOD_Leukemia

Explore this box plot interactively →