DCTN5

Across TCGA patient cohorts, DCTN5 protein abundance is significantly associated with the RNA expression of many other genes, with 14,526 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DCTN5-associated genes across cancer lineages are CDKN3, ACSM5, and CCDC69. Each is linked with DCTN5 in more than 5 cancer types. Because this analysis shows association rather than direction, both DCTN5-to-partner and partner-to-DCTN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCTN5 versus CDKN3 in LUAD, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN5→partner) and Y-score (partner→DCTN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDKN3 →	-1.227	-0.138	<.001	<.001	3	6
GBM	ACSM5 →	+0.912	+0.277	<.001	<.001	3	5
LSCC	CCDC69 →	+0.869	+0.173	<.001	<.001	3	5
LUAD	STK16P1 →	-0.737	-0.122	<.001	.002	2	6
UCEC	GINS1 →	-1.190	-0.266	<.001	<.001	3	5
LUAD	MYBL2 →	-1.278	-0.124	.002	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,526 associations by consensus.

DCTN5 vs CDKN3 — LUAD

Explore this scatter interactively →