DCTN5

Across TCGA cell cohorts, DCTN5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,792 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DCTN5-associated GO terms across cancer lineages are Positive regulation of macrophage proliferation, Regulation of chromatin organization, and Symbiont-mediated disruption of host cell PML body. Each is linked with DCTN5 in more than 13 cancer types. Because this analysis shows association rather than direction, both DCTN5-to-partner and partner-to-DCTN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of macrophage proliferation grouped by DCTN5-low versus DCTN5-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN5→partner) and Y-score (partner→DCTN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of macrophage proliferation →	+0.200	+1.149	<.001	<.001	3	14
BONE	Regulation of chromatin organization →	+0.119	+0.609	<.001	.001	3	14
LUNG_NSCLC_LUSC	Symbiont-mediated disruption of host cell PML body →	+0.121	+1.100	.001	<.001	3	13
SOFT_TISSUE	Nuclear export →	+0.089	+0.948	<.001	.003	3	12
STOMACH	Cytosolic transport →	+0.073	+0.792	.009	.002	3	11
BONE	Transcription initiation-coupled chromatin remodeling →	+0.071	+0.629	.004	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,792 associations by consensus.

Positive regulation of macrophage proliferation by DCTN5 expression — BREAST

Explore this box plot interactively →