DCTN4

Across TCGA patient cohorts, DCTN4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,500 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DCTN4-associated proteins across cancer lineages are TNFAIP8, KDM3B, and MAPK9. Each is linked with DCTN4 in more than 4 cancer types. Because this analysis shows association rather than direction, both DCTN4-to-partner and partner-to-DCTN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCTN4 versus TNFAIP8 in GBM, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN4→partner) and Y-score (partner→DCTN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TNFAIP8 →	-0.440	-0.170	.001	.003	3	5
GBM	KDM3B →	+0.266	+0.230	<.001	.003	3	5
BRCA	MAPK9 →	+0.357	+0.647	<.001	<.001	3	5
LUAD	NPM1 →	+0.236	+0.286	<.001	<.001	3	4
GBM	PHAX →	+0.254	+0.189	.001	.009	3	4
BRCA	RASA1 →	+0.242	+0.479	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,500 associations by consensus.

DCTN4 vs TNFAIP8 — GBM

Explore this scatter interactively →