DCTN4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DCTN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,898 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible DCTN4-associated GO terms across cancer lineages are Golgi organization, Organelle transport along microtubule, and Protein polyubiquitination. Each is linked with DCTN4 in more than 11 cancer types. Because this analysis shows association rather than direction, both DCTN4-to-partner and partner-to-DCTN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi organization grouped by DCTN4-low versus DCTN4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN4→partner) and Y-score (partner→DCTN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHGolgi organization →+0.087+0.633<.001.001312
LUNG_SCLCOrganelle transport along microtubule →+0.058+0.484.001.004312
UPPER_AERODIGESTIVE_TRACTProtein polyubiquitination →+0.033+0.505.004.001310
STOMACHGolgi vesicle transport →+0.090+0.627<.001.001310
LIVERPhosphatidylinositol dephosphorylation →+0.079+0.518<.001.001310
LUNG_SCLCRegulation of microtubule depolymerization →+0.079+0.576.003.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,898 associations by consensus.

Golgi organization by DCTN4 expression — STOMACH

Box plot of Golgi organization in DCTN4-low vs DCTN4-high samples in STOMACH.

Explore this box plot interactively →

Exploration