DCTN3

Across TCGA pan-cancer cohorts, DCTN3 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DCTN3 data layer compared with 27 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher DCTN3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DCTN3 expression acts as an unfavorable survival marker.

STAD, UCEC, and COAD are the cancer types where DCTN3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.001	0.688	<.001	48	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
COAD	OS	Median	II,III,IV	0.464	0.854	.016	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DCTN3–STAD (OS)

Open the STAD breakdown →