DCTN3

Across TCGA patient cohorts, DCTN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,851 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DCTN3-associated proteins across cancer lineages are VCP, PDIA6, and BAG1. Each is linked with DCTN3 in more than 4 cancer types. Because this analysis shows association rather than direction, both DCTN3-to-partner and partner-to-DCTN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCTN3 versus VCP in PDAC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN3→partner) and Y-score (partner→DCTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	VCP →	+0.328	+0.368	<.001	<.001	3	5
BRCA	PDIA6 →	-0.431	-0.444	<.001	<.001	3	5
BRCA	BAG1 →	+0.322	+0.332	.002	<.001	3	5
OV	UBE2R2 →	+0.364	+0.436	.002	.002	3	5
LUAD	ACO1 →	+0.333	+0.283	<.001	.002	3	4
LSCC	STOML2 →	+0.699	+0.618	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,851 associations by consensus.

DCTN3 vs VCP — PDAC

Explore this scatter interactively →