DCTN3

Across TCGA patient cohorts, DCTN3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,128 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DCTN3-associated genes across cancer lineages are JAM2, SKA1, and NDC80. Each is linked with DCTN3 in more than 5 cancer types. Because this analysis shows association rather than direction, both DCTN3-to-partner and partner-to-DCTN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCTN3 versus JAM2 in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN3→partner) and Y-score (partner→DCTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	JAM2 →	+0.854	+0.309	<.001	<.001	3	6
BRCA	SKA1 →	-1.045	-0.258	<.001	<.001	3	6
HNSC	NDC80 →	-0.990	-0.149	<.001	.004	3	6
LUAD	TPX2 →	-1.228	-0.172	<.001	<.001	3	6
LUAD	KIF4A →	-0.829	-0.138	<.001	<.001	3	6
BRCA	CDC25C →	-0.745	-0.229	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,128 associations by consensus.

DCTN3 vs JAM2 — BRCA

Explore this scatter interactively →