DCTN3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DCTN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,649 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DCTN3-associated GO terms across cancer lineages are Regulation of glycolytic process through fructose-6-phosphate, Negative regulation of glycolytic process through fructose-6-phosphate, and Latent virus replication. Each is linked with DCTN3 in more than 12 cancer types. Because this analysis shows association rather than direction, both DCTN3-to-partner and partner-to-DCTN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glycolytic process through fructose-6-phosphate grouped by DCTN3-low versus DCTN3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN3→partner) and Y-score (partner→DCTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTRegulation of glycolytic process through fructose-6-phosphate →+0.124+0.647<.001.004313
URINARY_TRACTNegative regulation of glycolytic process through fructose-6-phosphate →+0.124+0.647<.001.004313
LUNG_SCLCLatent virus replication →+0.214+1.041<.001.001310
LUNG_SCLCRelease from viral latency →+0.214+1.041<.001.001310
URINARY_TRACTRegulation of ubiquitin protein ligase activity →+0.179+1.082<.001<.00138
URINARY_TRACTPositive regulation of anaphase-promoting complex-dependent catabolic process →+0.124+0.889.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,649 associations by consensus.

Regulation of glycolytic process through fructose-6-phosphate by DCTN3 expression — URINARY_TRACT

Box plot of Regulation of glycolytic process through fructose-6-phosphate in DCTN3-low vs DCTN3-high samples in URINARY_TRACT.

Explore this box plot interactively →

Exploration