DCTN2

Across TCGA patient cohorts, DCTN2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,722 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DCTN2-associated genes across cancer lineages are FANCA, TPX2, and SKA1. Each is linked with DCTN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both DCTN2-to-partner and partner-to-DCTN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCTN2 versus FANCA in HNSC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN2→partner) and Y-score (partner→DCTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FANCA →	-0.730	-0.233	<.001	<.001	3	8
LUAD	TPX2 →	-0.960	-0.117	<.001	<.001	3	8
LUAD	SKA1 →	-0.978	-0.168	<.001	<.001	3	8
HNSC	DUTP2 →	-0.849	-0.160	.004	.009	3	7
HNSC	MCM4 →	-0.905	-0.228	<.001	<.001	3	7
HNSC	ASF1B →	-0.802	-0.156	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,722 associations by consensus.

DCTN2 vs FANCA — HNSC

Explore this scatter interactively →