DCTN2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DCTN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,158 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCTN2-associated GO terms across cancer lineages are Post-Golgi vesicle-mediated transport, Organelle transport along microtubule, and Golgi vesicle transport. Each is linked with DCTN2 in more than 10 cancer types. Because this analysis shows association rather than direction, both DCTN2-to-partner and partner-to-DCTN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-Golgi vesicle-mediated transport grouped by DCTN2-low versus DCTN2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN2→partner) and Y-score (partner→DCTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYPost-Golgi vesicle-mediated transport →+0.071+0.653<.001<.001311
UPPER_AERODIGESTIVE_TRACTOrganelle transport along microtubule →+0.044+0.582.003.007311
BLOOD_LymphomaGolgi vesicle transport →+0.061+0.833<.001<.001311
OESOPHAGUSMacroautophagy →+0.057+0.487.009.009311
OESOPHAGUSVesicle cytoskeletal trafficking →+0.064+0.781.003.001310
STOMACHAutophagosome assembly →+0.054+0.547<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,158 associations by consensus.

Post-Golgi vesicle-mediated transport by DCTN2 expression — KIDNEY

Box plot of Post-Golgi vesicle-mediated transport in DCTN2-low vs DCTN2-high samples in KIDNEY.

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Exploration