DCTN1-AS1

Across TCGA pan-cancer cohorts, DCTN1-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated DCTN1-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher DCTN1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated DCTN1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and THCA show a favorable association.

BRCA, THCA, and DLBC are the cancer types where DCTN1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	II,III,IV	0.950	0.883	<.001	83	view →
THCA	DFS	Quartile	III,IV	0.929	0.295	.001	55	view →
DLBC	DFS	Median	IV	0.412	1.000	.006	52	view →
MESO	DFS	Tertile	All	0.189	0.365	.004	38	view →
CHOL	OS	Tertile	All	0.256	0.792	<.001	26	view →
ACC	OS	Median	All	0.471	0.745	.001	24	view →
KIRC	DFS	Median	IV	0.495	0.717	.021	21	view →
LUSC	OS	Median	All	0.714	0.607	.007	19	view →
LUAD	OS	Quartile	All	0.874	0.761	.007	18	view →
PAAD	OS	Tertile	All	0.192	0.496	.002	12	view →
SKCM	OS	Median	IV	0.787	0.282	.020	10	view →
PRAD	DFS	Quartile	All	0.716	0.915	.004	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

DCTN1-AS1–BRCA (OS)

Open the BRCA breakdown →