DCT

Across TCGA patient cohorts, DCT RNA expression is significantly associated with the protein abundance of many other proteins, with 8,736 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DCT-associated proteins across cancer lineages are OLFML1_S114, APEH_S187, and MNDA. Each is linked with DCT in more than 3 cancer types. Because this analysis shows association rather than direction, both DCT-to-partner and partner-to-DCT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCT versus OLFML1_S114 in CCRCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DCT→partner) and Y-score (partner→DCT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	OLFML1_S114 →	+0.760	+0.353	<.001	<.001	3	3
CCRCC	APEH_S187 →	-0.248	-0.399	<.001	.001	3	3
LSCC	MNDA →	-0.547	-0.192	<.001	<.001	3	3
LSCC	SMARCA2 →	+0.319	+0.149	<.001	<.001	3	3
GBM	GSTA4 →	+0.876	+0.996	<.001	<.001	3	3
UCEC	JPT2 →	-0.411	-0.529	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,736 associations by consensus.

DCT vs OLFML1_S114 — CCRCC

Explore this scatter interactively →