DCT

Across TCGA patient cohorts, DCT protein abundance is significantly associated with the RNA expression of many other genes, with 215 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DCT-associated genes across cancer lineages are ZKSCAN1, CMAS, and USP26. Each is linked with DCT in more than 1 cancer types. Because this analysis shows association rather than direction, both DCT-to-partner and partner-to-DCT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCT versus ZKSCAN1 in BRCA, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCT→partner) and Y-score (partner→DCT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZKSCAN1 →	+0.979	+0.738	.001	.005	3	1
BRCA	CMAS →	-0.467	-0.714	.004	.009	3	1
BRCA	USP26 →	+0.111	+0.739	.001	.005	3	1
BRCA	SKIL →	-0.588	-0.714	.002	.009	3	1
BRCA	ZNF365 →	-1.325	-0.591	.008	.004	3	1
BRCA	CASK →	-1.046	-0.888	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 215 associations by consensus.

DCT vs ZKSCAN1 — BRCA

Explore this scatter interactively →