DCST2

Across TCGA cell cohorts, DCST2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,345 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DCST2-associated GO terms across cancer lineages are Taurine biosynthetic process, Alkanesulfonate biosynthetic process, and Regulation of myoblast fusion. Each is linked with DCST2 in more than 12 cancer types. Because this analysis shows association rather than direction, both DCST2-to-partner and partner-to-DCST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Taurine biosynthetic process grouped by DCST2-low versus DCST2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCST2→partner) and Y-score (partner→DCST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Taurine biosynthetic process →	+0.954	+0.804	.004	.009	3	13
UPPER_AERODIGESTIVE_TRACT	Alkanesulfonate biosynthetic process →	+0.954	+0.804	.004	.009	3	13
KIDNEY	Regulation of myoblast fusion →	+0.113	+0.610	<.001	<.001	3	13
OESOPHAGUS	Sperm motility →	-0.105	-0.971	.004	.001	3	12
OESOPHAGUS	Flagellated sperm motility →	-0.105	-0.971	.004	.001	3	12
OESOPHAGUS	Cilium movement involved in cell motility →	-0.133	-1.281	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,345 associations by consensus.

Taurine biosynthetic process by DCST2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →