DCPS

Across TCGA patient cohorts, DCPS mutation is significantly associated with the RNA expression of many other genes, with 2,196 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCPS-associated genes across cancer lineages are TSPY16P, SNORD62A, and LINC01072. Each is linked with DCPS in more than 1 cancer types. Because this analysis shows association rather than direction, both DCPS-to-partner and partner-to-DCPS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY16P grouped by DCPS-low versus DCPS-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCPS→partner) and Y-score (partner→DCPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TSPY16P →	+0.023	+4.673	<.001	.001	3	2
UCEC	SNORD62A →	+0.439	+1.867	<.001	.002	3	2
UCEC	LINC01072 →	+0.126	+2.582	<.001	<.001	3	2
BLCA	MIR516A1 →	+0.531	+4.314	<.001	.009	3	2
UCEC	YTHDF3-AS1 →	+0.593	+2.931	<.001	<.001	3	1
UCEC	CCL5 →	+0.992	+2.923	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,196 associations by consensus.

TSPY16P by DCPS expression — UCEC

Explore this box plot interactively →