DCP2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DCP2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCP2-associated genes across cancer lineages are TMEM196, CDR1, and GSG1L2. Each is linked with DCP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCP2-to-partner and partner-to-DCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM196 grouped by DCP2-low versus DCP2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCP2→partner) and Y-score (partner→DCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaTMEM196 →+0.036+3.874<.001.00531
BLOOD_LeukemiaCDR1 →+0.047+4.060.001.00331
BLOOD_LeukemiaGSG1L2 →+0.034+4.384<.001.00631
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TMEM196 by DCP2 expression — BLOOD_Leukemia

Box plot of TMEM196 in DCP2-low vs DCP2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration