DCP1B

Across TCGA pan-cancer cohorts, DCP1B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DCP1B data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher DCP1B mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DCP1B expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

LSCC, HNSC, and GBM are the cancer types where DCP1B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	II,III,IV	0.585	0.952	.002	36	view →
HNSC	OS	Quartile	IV	0.429	0.850	.001	30	view →
GBM	OS	Tertile	All	0.619	0.377	.002	26	view →
COAD	DFS	Median	All	0.907	1.000	.036	12	view →
LUAD	OS	Median	II,III,IV	0.893	0.453	.026	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DCP1B–LSCC (OS)

Open the LSCC breakdown →