DCP1A

Across TCGA pan-cancer cohorts, DCP1A mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DCP1A data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DCP1A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DCP1A expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

UCEC, LUAD, and CCRCC are the cancer types where DCP1A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.783	0.929	.014	18	view →
LUAD	DFS	Tertile	III,IV	1.000	0.412	.013	14	view →
CCRCC	DFS	Quartile	All	1.000	0.657	.002	5	view →
PDAC	OS	Tertile	III,IV	0.583	0.320	.034	2	view →
LSCC	DFS	Median	All	0.611	0.869	.044	2	view →
HNSC	OS	Median	III,IV	0.777	0.606	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DCP1A–UCEC (DFS)

Open the UCEC breakdown →