DCN

Across TCGA patient cohorts, DCN RNA expression is significantly associated with the protein abundance of many other proteins, with 23,237 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DCN-associated proteins across cancer lineages are LUM, TPM1, and TPM2. Each is linked with DCN in more than 9 cancer types. Because this analysis shows association rather than direction, both DCN-to-partner and partner-to-DCN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCN versus LUM in GBM, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DCN→partner) and Y-score (partner→DCN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LUM →	+1.196	+1.272	<.001	<.001	3	10
UCEC	TPM1 →	+0.633	+1.379	<.001	<.001	3	10
CCRCC	TPM2 →	+1.008	+1.887	<.001	<.001	3	10
UCEC	CALD1 →	+0.934	+1.503	<.001	<.001	3	10
BRCA	OLFML3 →	+0.841	+1.631	<.001	<.001	3	10
LSCC	PCOLCE →	+0.860	+1.141	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,237 associations by consensus.

DCN vs LUM — GBM

Explore this scatter interactively →