DCN

Across TCGA patient cohorts, DCN protein abundance is significantly associated with the RNA expression of many other genes, with 16,502 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DCN-associated genes across cancer lineages are CRISPLD2, SFRP4, and MGP. Each is linked with DCN in more than 9 cancer types. Because this analysis shows association rather than direction, both DCN-to-partner and partner-to-DCN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCN versus CRISPLD2 in OV, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCN→partner) and Y-score (partner→DCN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CRISPLD2 →	+1.547	+0.763	<.001	<.001	3	10
OV	SFRP4 →	+2.230	+0.900	<.001	<.001	3	10
COAD	MGP →	+1.928	+0.772	<.001	<.001	3	10
CCRCC	C7 →	+2.111	+0.790	<.001	<.001	3	10
BRCA	GLT8D2 →	+1.124	+0.950	<.001	<.001	3	10
OV	PTGIS →	+1.623	+0.841	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,502 associations by consensus.

DCN vs CRISPLD2 — OV

Explore this scatter interactively →